Aligning Coding DNA in the Presence of Frame-Shift Errors
نویسنده
چکیده
Abs t rac t . The problem of aligning two DNA sequences with respect to the fact that they are coding for proteins is discussed. Criteria for a good alignment of coding DNA, together with an algorithm that satisfies them, are presented. The algorithm is robust against frame-shifts and forgiving towards silent substitutions. The important choice of objective function is examined and several variants are proposed.
منابع مشابه
P-85: How a Frame Shift Caused by a Single Base Deletion In SEPT12 Gene Shed Lights As a Polymorphism
Background: Septins are members of highly conserved polymerizing GTP binding proteins well described in the animal kingdom. 14 Septin proteins have been characterized in humans (SEPT1-SEPT14), some of which are tissue-specific. All of 14 genome-mapped human septins contain a highly conserved central GTP-binding domain which is very critical in GTPase signaling properties as well as oligomerizat...
متن کاملاصلاح ردیاب انتقال متوسط برای ردگیری هدف با الگوی تابشی متغیر
The mean shift algorithm is one of the popular methods in visual tracking for non-rigid moving targets. Basically, it is able to locate repeatedly the central mode of a desirable target. Object representation in mean shift algorithm is based on its feature histogram within a non-oriented individual kernel mask. Truly, adjusting of the kernel scale is the most critical challenge in this method. ...
متن کاملچشم انداز در عمل: خط‌مشی و رویه‌های کدگذاری بالینی
Introduction: Every health organization life depends on its correct coding system. One of the best tools in collecting correct and valid data is to make a clinical coding and procedures. Clinical Coding policy and procedures, in face of personals changes causes stability, and continues the clinical coding and provide a frame for decision making and doing duties . Methods: This research was carr...
متن کاملDiagnostic Measures in Ridge Regression Model with AR(1) Errors under the Stochastic Linear Restrictions
Outliers and influential observations have important effects on the regression analysis. The goal of this paper is to extend the mean-shift model for detecting outliers in case of ridge regression model in the presence of stochastic linear restrictions when the error terms follow by an autoregressive AR(1) process. Furthermore, extensions of measures for diagnosing influential observations are ...
متن کاملمقاوم سازی بردار حرکت در برابر خطای کانال جهت بهبود کیفیت ویدیوی دریافتی
According to progress of technology during the recent decades, video transmission through a wireless channel has found high demands. In this field, several methods have been proposed to improve video quality. Appearing error in motion vector values is one of the most important factors which can affect the video quality. In case of creating errors in motion vector, the synthesized video frames a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 1997